Large Granular Lymphocytic Leukemia

A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.

Also Known As:

Leukemia, Large Granular Lymphocytic; Aggressive NK Cell Leukemia; Aggressive Natural Killer Cell Leukemia; LGL Leukemia; Large Granular Lymphocyte Leukemia; Large Granular Lymphocytosis; Leukemia, LGL; Leukemia, NK-LGL; Leukemia, T-LGL; Lymphoproliferative Disease of Granular Lymphocytes; Lymphoproliferative Disease of Large Granular Lymphocytes; NK-Cell Large Granular Lymphocytic Leukemia; NK-LGL Leukemia; T-Cell Large Granular Lymphocyte Leukemia; T-LGL Leukemia; Granular Lymphocytoses, Large; Granular Lymphocytosis, Large; LGL Leukemias; Large Granular Lymphocytoses; Leukemia, NK LGL; Leukemia, T Cell Large Granular Lymphocytic; Leukemia, T LGL; Leukemias, LGL; Leukemias, NK-LGL; Leukemias, T-LGL; Lymphocytoses, Large Granular; Lymphocytosis, Large Granular; NK Cell Large Granular Lymphocytic Leukemia; NK LGL Leukemia; NK-LGL Leukemias; T Cell Large Granular Lymphocyte Leukemia; T Cell Large Granular Lymphocytic Leukemia; T LGL Leukemia; T-LGL Leukemias; Leukemia, Lymphocytic, Large Granular; Leukemia, Natural Killer Cell Large Granular Lymphocytic; Leukemia, T-Cell Large Granular Lymphocytic; Natural Killer Cell Large Granular Lymphocytic Leukemia; T-Cell Large Granular Lymphocytic Leukemia

Neoplasms: 1361496
- Neoplasms by Histologic Type: 2
  - Leukemia: 59371
    - Lymphoid Leukemia: 1721
      - T-Cell Leukemia: 2805
        Large Granular Lymphocytic Leukemia: 405
Hemic and Lymphatic Diseases: 7
- Hematologic Diseases: 3445
  - Leukemia: 59371
    - Lymphoid Leukemia: 1721
      - T-Cell Leukemia: 2805
        Large Granular Lymphocytic Leukemia: 405
- Lymphatic Diseases: 96
  - Lymphoproliferative Disorders: 4321
    - Lymphoid Leukemia: 1721
      - T-Cell Leukemia: 2805
        Large Granular Lymphocytic Leukemia: 405
Immune System Diseases: 4430
- Immunoproliferative Disorders: 29
  - Lymphoproliferative Disorders: 4321
    - Lymphoid Leukemia: 1721
      - T-Cell Leukemia: 2805
        Large Granular Lymphocytic Leukemia: 405

R Kothapalli Selected Research

R Kothapalli Research Topics

Disease

Drug/Important Bio-Agent (IBA)